As an Assistant Professor at Seton Hall, I am excited to share my passion for Biology in the classroom and in the lab. I am fascinated by how cells, especially stem cells, communicate to maintain normal health. The goal of my research is to understand how stem cells decide whether to remain stem cells or differentiate into specialized cells like muscles, neurons, blood cells, etc. Understanding stem cell behavior will allow us to develop novel cell-based therapies against diseases like cancers, developmental defects, and various degenerative disorders. My research uses stem cells residing in the germ line of the microscopic roundworm C. elegans as a model system to investigate cellular networks that regulate the accumulation of stem cells during development and their maintenance later in life.
- Postdoctoral Training, New York University School of Medicine
- Graduate Training (Ph.D.), University of North Carolina at Chapel Hill
- Undergraduate Training (B.S.), State University of New York College at Brockport
- Roy et al. Functional Interactions Between rsks-1/S6K, glp-1/Notch, and Regulators of Caenorhabditis elegans Fertility and Germline Stem Cell Maintenance 2018 G3 doi: 10.1534/g3.118.200511
- Roy et al. Cell cycle features of C. elegans germline stem/progenitor cells vary temporally and spatially 2016 Developmental Biology doi: 10.1016/j.ydbio.2015.10.031
- Roy et al. mTOR inhibitors block Kaposi sarcoma growth by inhibiting essential autocrine growth factors and tumor angiogenesis 2013 Cancer Research doi: 10.1158/0008-5472.CAN-12-1851
- Roy et al. Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines 2011 Blood doi: 10.1182/blood-2010-12-323659
- Roy and Dittmer. Phosphatase and tensin homolog on chromosome 10 is phosphorylated in primary effusion lymphoma and Kaposi's sarcoma 2011 American Journal of Pathology doi: 10.1016/j.ajpath.2011.06.017
Complete list of publications available here.